Wednesday, April 1, 2020

Anosmia


The team suspected that nerve cells responsible for smell may be damaged by the virus and so went looking through datasets to see if the cells contained ACE2 and one other protein that helps SARS-CoV-2 get inside cells. This is where the surprise came.

The datasets suggest its not nerve cells that SARS-CoV-2 enters, but a different subset of "epithelial" cells -- the cells on the surfaces inside your nose.  Whether or not COVID-19 can cause a permanent loss of smell is still to be determined. Imagine a world without smell.

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